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Plexus VitalBiome™

Plexus VitalBiome™

17 reviews
Healthy gut. Happy mind.™

VitalBiome is a revolutionary probiotic with clinically-demonstrated ingredients that help improve your health and your mood! Its exceptional formula delivers 8 diverse probiotic strains that reduce feelings of stress and anxiety, reduce GI distress, and rebalance your gut microflora, dramatically improving your health and happiness.*

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  • Helps reduce feelings of stress & improve mood*
  • Helps reduce GI distress*
  • Stabilizes stress hormones & promotes relaxation*
  • Supports a healthy immune system*
  • Helps relieve bloating & bowel discomfort*
  • 20 billion CFUˆ
  • 8 clinically-documented strains
  • Delayed release capsule
  • PlexiPak™ bottle to safeguard probiotics
  • Gluten Free, 100% Vegetarian, Non-GMO

ˆAt time of manufacture

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Why do I need a probiotic supplement?

Things like poor diet, medications, lack of exercise, and even stress directly impact the number of good microbes found in our microbiome. This imbalance keeps us from enjoying life at its fullest. Reseeding our GI tract with VitalBiome™ helps restore balance and helps our body functions optimally.*

How does VitalBiome “Seed” the gut?

The majority of American’s experience dysbiosis which means that their gut is out of balance. To help get your gut back in balance you need to weed, seed, feed and protect your gut. VitalBiome helps seed your gut with 20 Billion beneficial microbes that help crowd out unhealthy ones making your gut more healthy. The clinically studied strains selected in VitalBiome provide significant health benefits, and were also selected because of their ability to survive the journey through your GI tract and be able to adhere to the gut wall.*

What are the strains used in VitalBiome?

VitalBiome contains 8 beneficial probiotic strains that include: Lactobacillus helveticus (R0052), Bifidobacterium longum (R0175), Bacillus coagulans (MTCC 5856), Bifidobacterium lactis (Bi-04), Saccharomyces boulardii (I-3799), Bifidobacterium lactis (Bi-07), Lactobacillus plantarum (LP-115), and Lactobacillus acidophilus (NCFM).

What is the difference between VitalBiome and Probio5?

VitalBiome is a probiotic supplement that is formulated to SEED your gut with significant levels of good microbes. It contains 20 billion CFUˆ (8 different probiotic strains) that help reduce feelings of stress and anxiety, improve mood, reduce GI distress, bloating, and discomfort, and help improve immune health. VitalBiome utilizes clinically studied probiotic strains protected in a delayed release capsule. Probio5 is a corrective agent with a powerful enzyme blend that is designed to help keep intestinal yeast in balance to help your keep your gut microbiome healthy.  ProBio5  contains 2 billion CFUˆ (5 different probiotic strains).*

Can I take both VitalBiome and Probio5?

Yes. VitalBiome and Probio5 can both be taken as part of your daily health regimen. VitalBiome is best taken in the morning on an empty stomach or between meals. ProBio5 works best to help keep intestinal yeast in balance when taken on an empty stomach at night. VitalBiome in the morning and Probio5 at night.

Can I take VitalBiome with Slim?

Yes, VitalBiome can be taken with Slim. However unlikely, individuals who aren’t used to taking probiotics or prebiotics may experience some side effects such as gas or bloating. To minimize these possible effects, start taking ½ a dose of Slim with VitalBiome. Slowly increase the amount of Slim each day until you are at a full daily dose. Consult a physician if you have additional concerns with taking a probiotic.

Can I take VitalBiome with TriPlex™?

Yes, VitalBiome is a perfect companion for TriPlex. We suggest taking VitalBiome in the morning and Probio5 at night. Bio Cleanse and Slim can be taken as directed.

When can I expect to see results?

Results can vary from individual to individual, but participants of the strain clinical tests reported reduced feelings of stress, improved mood, and improved digestive health after 30 days.*

What is CFU count and is it important?

CFU, or colony-forming units, is a term often seen in conjunction with probiotic supplements. It is a measurement of viable microbial cells that can replicate to form one visible colony. CFU count is only as important as the clinical study it is tied to. VitalBiome was formulated to deliver clinically demonstrated CFU counts at the time of expiration.

What is the CFU count of VitalBiome?

VitalBiome contains over 20 billion CFU per capsule at the time of manufacture and delivers clinically tested levels of probiotics through the time of expiration.

What is a delayed-release capsule and why is it important?

VitalBiome utilizes a delayed-release capsule that has been engineered to better withstand the harsh acidic conditions found in the stomach. Studies show these capsules take 45 minutes to dissolve while traditional capsules are less than 30 minutes. Protecting probiotics from these harsh conditions insures the maximum number of live probiotics make it to the intestinal tract.

What is a PlexiPak™?

PlexiPak is a specialized bottle designed for probiotic products. Probiotics are very sensitive to moisture. The PlexiPak’s unique, desiccant lined walls protect probiotics from moisture so they remain active.

Will I experience any side effects with VitalBiome?

No, however those not used to consuming higher doses of probiotics may experience some side effects such as gas and bloating. Interestingly, this is good as it indicates the good microbes are crowding out bad microbes and improving your GI tract. Be sure to drink plenty of water and give it some time. Side effects usually pass within a few days as your GI tract gets rebalanced with more good microbiota. Consult a physician if you have concerns with taking probiotic supplements.*

When is the best time to take VitalBiome?

VitalBiome can be taken at any time, but we suggest taking the product when stomach acid is at its lowest levels, generally between meals or first thing in the morning.

Do I need to refrigerate VitalBiome?

It is not necessary to refrigerate VitalBiome. While the general rule for probiotics storage is the colder the better, VitalBiome uses a protective PlexiPack™ bottle, which better protects the product from oxygen and moisture. VitalBiome is guaranteed to deliver clinically efficacious amounts of probiotics if stored below 70 degrees.

Can I take half a dose or multiple capsules?

VitalBiome was formulated to deliver product claims based on individual strain clinical testing results. Therefore, we recommend taking the suggested dose of one capsule per day.

I don’t like swallowing pills; can I break open the capsule to take it?

While not recommended, you can open the capsule to consume. You simply lose the benefits of added stomach acid protection that the capsule provides.

Does VitalBiome contain any of the eight most common food allergens (Dairy, Egg, Peanut, Soy, Shellfish, Tree-Nut, and Wheat)?

Yes, it contains dairy and soy.

Which VitalBiome ingredient contains dairy?

Bifidobacterium longum (R0175) utilizes dairy products during the fermentation process and is manufactured in a facility that processes dairy ingredients. The clinically demonstrated benefits this strain provides are so incredible this strain was added to the formula. Anyone with dairy allergies should consult a physician prior to using VitalBiome.

Which VitalBiome ingredients contain soy?

Lactobacillus helveticus (R0052) and Bifidobacterium longum (R0175) utilize soy products during the fermentation/manufacturing process. They, along with brown rice flour, are also produced in a facility that processes soy containing ingredients. The clinically demonstrated benefits these strains provide are so incredible these strains were added to the formula. Anyone with soy allergies should consult a physician prior to using VitalBiome.

What is the benefit of using probiotic yeast?

VitalBiome contains Saccharomyces Boulardii (I-3799), a hardy probiotic yeast that can survive the harsh journey to the intestinal tract where is shown to supports digestive health.

Does VitalBiome contain magnesium stearate or silicon dioxide?

No, VitalBiome contains no magnesium stearate or silicon dioxide.

ˆAt time of manufacture

Average Rating: 4.5 out of 5 (17 votes)
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wow plexus is awsome

5 days ago


Been taking this for 2 weeks and have already seen an improvement in my digestion and have had a decrease in stomach pain and rumbling.

2 weeks ago

I’ve been taking this for almost a month and it has really messed my stomach up and given me bad acid reflux, which I have never experienced before.

2 weeks ago
Julie Carson

Definitely noticed a huge difference in about a week and a half. I’ve been taking this product now for 3 weeks. I don’t feel nearly as stressed out!

2 weeks ago


I’ve been taking plexus vitalbiome for over a week and my stomach is a mess. Not feeling calmer at all. Very disappointed.

4 weeks ago

Good product

1 month ago

Started 3 weeks ago amazing feeling less anxious . Mental stamina improved. Better focus My gut feels settled. Coping with challenges

1 month ago
Erin McCullough

I have been taking Vitalbiome for 6 days, best mood I have been in, in all of my life. Even my husband and kids are commenting on my GOOD relaxed mood

2 months ago
Jackie Mac


Amazed at how quickly this powerpill goes to work. I hear some rumbling in my tummy and the stress/emotions melt away. I am loving it.

2 months ago
Katie Chronister


This product is ABSOLUTELY the real deal. I’ve been taking it for 2 weeks and my husband for 1 week and we are both noticeably more calm and happy!!

2 months ago

I’ve been taking VitalBiome for about 4 days … I am completely blown away with how effective this product is. I was skeptical, but this is REAL!

2 months ago

I have experienced an overall calming and pleasant mood. Very noticeable when normal stressful situations arise. Not anxious. I feel the difference!!

2 months ago
Shannon E.

I have been taking this product for two weeks now and my husband just complimented my mood because I am a lot happier and less stressed. Win, win!

2 months ago

This is the best chill pill a momma of 5 could ask for. Calm and Chilled and HAPPY!

2 months ago


My gut is the happiest it has EVER been…and so am I! THANK YOU, Plexus!!!

2 months ago


VitalBiome is one of my new favorite supplements! I see an improvement in my happiness & mood and a decrease in my stress and anxiety! Love it!

2 months ago


I’ve been taking this for 5 days and have always had constipation issues (especially the week before my cycle) … let me tell you those days are over

3 months ago
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*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.